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Plasmodium falciparum uses a key functional site in complement receptor type-1 for invasion of human erythrocytes

The Plasmodium falciparum adhesin PfRh4 binds to complement receptor type-1 (CR1) on human erythrocytes and mediates a glycophorin-independent invasion pathway. CR1 is a complement regulator and immune-adherence receptor on erythrocytes required for shuttling of C3b/C4b-opsonized particles to liver...

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Detaylı Bibliyografya
Asıl Yazarlar: Tham, Wai-Hong, Schmidt, Christoph Q., Hauhart, Richard E., Guariento, Mara, Tetteh-Quarcoo, Patience B., Lopaticki, Sash, Atkinson, John P., Barlow, Paul N., Cowman, Alan F.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158720/
https://ncbi.nlm.nih.gov/pubmed/21685372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-03-341305
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