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Methods development for Analysis of Partially Deglycosylated Proteins and Application to an HIV Envelope Protein Vaccine Candidate

The work presented herein describes the first comprehensive analysis of a partially deglycosylated HIV vaccine candidate envelope protein (Env). The Env, JRFL gp140 ΔCF, with 27 potential glycosylation sites, was partially deglycosylated with PNGase F as part of a strategy to generate a more immunog...

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Библиографические подробности
Главные авторы: Go, Eden P., Hewawasam, Geetha S., Ma, Ben J., Liao, Hua-Xin, Haynes, Barton F., Desaire, Heather
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158616/
https://ncbi.nlm.nih.gov/pubmed/21860603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijms.2010.11.009
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