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Evidence for the Role of Histamine H3 Receptor in Alcohol Consumption and Alcohol Reward in Mice

Recent research suggests that histamine H3 receptor (H3R) antagonism may diminish motivational aspects of alcohol dependence. We studied the role of H3Rs in alcohol-related behaviors using H3R knockout (KO) mice and ligands. H3R KO mice consumed less alcohol than wild-type (WT) mice in a two-bottle...

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Detalhes bibliográficos
Main Authors: Nuutinen, Saara, Lintunen, Minnamaija, Vanhanen, Jenni, Ojala, Tiia, Rozov, Stanislav, Panula, Pertti
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158320/
https://ncbi.nlm.nih.gov/pubmed/21654737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2011.90
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