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The Reduction of R1, a Novel Repressor Protein for Monoamine Oxidase A, in Major Depressive Disorder

The novel transcriptional repressor protein, R1 (JPO2/CDCA7L/RAM2), inhibits monoamine oxidase A (MAO A) gene expression and influences cell proliferation and survival. MAO A is implicated in several neuropsychiatric illnesses and highly elevated in major depressive disorder (MDD); however, whether...

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Detalhes bibliográficos
Main Authors: Johnson, Shakevia, Stockmeier, Craig A, Meyer, Jeffrey H, Austin, Mark C, Albert, Paul R, Wang, Junming, May, Warren L, Rajkowska, Grazyna, Overholser, James C, Jurjus, George, Dieter, Lesa, Johnson, Chandra, Sittman, Donald B, Ou, Xiao-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158311/
https://ncbi.nlm.nih.gov/pubmed/21654740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2011.105
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