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Dissecting Therapeutic Resistance to RAF Inhibition in Melanoma by Tumor Genomic Profiling
A detailed understanding of the mechanisms by which tumors acquire resistance to targeted anticancer agents should speed the development of treatment strategies with lasting clinical efficacy. RAF inhibition in BRAF-mutant melanoma exemplifies the promise and challenge of many targeted drugs; althou...
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| Autores principales: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society of Clinical Oncology
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3157968/ https://ncbi.nlm.nih.gov/pubmed/21383288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2010.33.2312 |
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