Mouse models of hepatocarcinogenesis: What can we learn for the prevention of human hepatocellular carcinoma?

There is growing evidence that chronic inflammatory processes are involved in triggering the sequence from chronic liver injury to liver fibrosis, ultimately leading to liver cancer. In the last years this process has been recapitulated in a growing number of different mouse models. However, it has...

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Bibliographic Details
Main Authors: Vucur, Mihael, Roderburg, Christoph, Bettermann, Kira, Tacke, Frank, Heikenwalder, Mathias, Trautwein, Christian, Luedde, Tom
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2010
Subjects:
Research Perspectives
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157729/
https://ncbi.nlm.nih.gov/pubmed/21307402
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