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Neuropeptide pituitary adenylate cyclase-activating polypeptide (PACAP) slows down Alzheimer's disease-like pathology in amyloid precursor protein-transgenic mice
Pituitary adenylate cyclase-activating polypeptide (PACAP) has neuroprotective and neurotrophic properties and is a potent α-secretase activator. As PACAP peptides and their specific receptor PAC1 are localized in central nervous system areas affected by Alzheimer's disease (AD), this study aim...
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Główni autorzy: | , , , , , , , , , |
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Format: | Artigo |
Język: | Inglês |
Wydane: |
Federation of American Societies for Experimental Biology
2011
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Hasła przedmiotowe: | |
Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3157688/ https://ncbi.nlm.nih.gov/pubmed/21593432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-180133 |
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