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Computation of Absolute Hydration and Binding Free Energy with Free Energy Perturbation Distributed Replica-Exchange Molecular Dynamics (FEP/REMD)

Distributed Replica (REPDSTR) is a powerful parallelization technique enabling simulations of a group of replicas in a parallel/parallel fashion, where each replica is distributed to different nodes of a large cluster [Theor. Chem. Acc. 109: 140 (2003)]. Here, we use the framework provided by REPDST...

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Detalhes bibliográficos
Main Authors: Jiang, Wei, Hodoscek, Milan, Roux, Benoît
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157678/
https://ncbi.nlm.nih.gov/pubmed/21857812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ct900223z
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