The potential impact of RV144-like vaccines in rural South Africa: a study using the STDSIM microsimulation model

BACKGROUND: The only successful HIV vaccine trial to date is the RV144 trial of the ALVAC/AIDSVAX vaccine in Thailand, which showed an overall incidence reduction of 31%. Most cases were prevented in the first year, suggesting a rapidly waning efficacy. Here, we predict the population level impact a...

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Hlavní autoři: Hontelez, Jan AC, Nagelkerke, Nico, Bärnighausen, Till, Bakker, Roel, Tanser, Frank, Newell, Marie-Louise, Lurie, Mark N, Baltussen, Rob, de Vlas, Sake J
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157643/
https://ncbi.nlm.nih.gov/pubmed/21703321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2011.06.059
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