One-Step Preservation of Phosphoproteins and Tissue Morphology at Room Temperature for Diagnostic and Research Specimens

BACKGROUND: There is an urgent need to measure phosphorylated cell signaling proteins in cancer tissue for the individualization of molecular targeted kinase inhibitor therapy. However, phosphoproteins fluctuate rapidly following tissue procurement. Snap-freezing preserves phosphoproteins, but is un...

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Detalhes bibliográficos
Main Authors: Mueller, Claudius, Edmiston, Kirsten H., Carpenter, Calvin, Gaffney, Eoin, Ryan, Ciara, Ward, Ronan, White, Susan, Memeo, Lorenzo, Colarossi, Cristina, Petricoin, Emanuel F., Liotta, Lance A., Espina, Virginia
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157466/
https://ncbi.nlm.nih.gov/pubmed/21858221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023780
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