The Pathologic Effect of a Novel Neomorphic Fgf9(Y162C) Allele Is Restricted to Decreased Vision and Retarded Lens Growth

Fibroblast growth factor (Fgf) signalling plays a crucial role in many developmental processes. Among the Fgf pathway ligands, Fgf9 (UniProt: P54130) has been demonstrated to participate in maturation of various organs and tissues including skeleton, testes, lung, heart, and eye. Here we establish a...

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Main Authors: Puk, Oliver, Möller, Gabriele, Geerlof, Arie, Krowiorz, Kathrin, Ahmad, Nafees, Wagner, Sibylle, Adamski, Jerzy, de Angelis, Martin Hrabé, Graw, Jochen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157460/
https://ncbi.nlm.nih.gov/pubmed/21858205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023678
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