Apoptosis Induced by Piroxicam plus Cisplatin Combined Treatment Is Triggered by p21 in Mesothelioma

BACKGROUND: Malignant mesothelioma (MM) is a rare, highly aggressive tumor, associated to asbestos exposure. To date no chemotherapy regimen for MM has proven to be definitively curative, and new therapies for MM treatment need to be developed. We have previously shown in vivo that piroxicam/cisplat...

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Main Authors: Baldi, Alfonso, Piccolo, Maria Teresa, Boccellino, Maria Rosaria, Donizetti, Aldo, Cardillo, Irene, La Porta, Raffaele, Quagliuolo, Lucio, Spugnini, Enrico P., Cordero, Francesca, Citro, Gennaro, Menegozzo, Massimo, Calogero, Raffaele A., Crispi, Stefania
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157425/
https://ncbi.nlm.nih.gov/pubmed/21858171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023569
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