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Eosinophils Contribute to IL-4 Production and Shape the T-Helper Cytokine Profile and Inflammatory Response in Pulmonary Cryptococcosis

Susceptibility to infection with Cryptococcus neoformans is tightly determined by production of IL-4. In this study, we investigated the time course of IL-4 production and its innate cellular source in mice infected intranasally with C. neoformans. We show that pulmonary IL-4 production starts surpr...

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Main Authors: Piehler, Daniel, Stenzel, Werner, Grahnert, Andreas, Held, Josephin, Richter, Lydia, Köhler, Gabriele, Richter, Tina, Eschke, Maria, Alber, Gottfried, Müller, Uwe
格式: Artigo
語言:Inglês
出版: American Society for Investigative Pathology 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157286/
https://ncbi.nlm.nih.gov/pubmed/21699881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.04.025
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