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TLR7 and TLR9 Trigger Distinct Neuroinflammatory Responses in the CNS

Toll-like receptors (TLRs) 7 and 9 recognize nucleic acid determinants from viruses and bacteria and elicit the production of type I interferons and proinflammatory cytokines. TLR7 and TLR9 are similar regarding localization and signal transduction mechanisms. However, stimulation of these receptors...

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Autori principali: Butchi, Niranjan B., Woods, Tyson, Du, Min, Morgan, Timothy W., Peterson, Karin E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157277/
https://ncbi.nlm.nih.gov/pubmed/21801870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.04.011
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