Microglia/Macrophages Migrate through Retinal Epithelium Barrier by a Transcellular Route in Diabetic Retinopathy: Role of PKCζ in the Goto Kakizaki Rat Model

Diabetic retinopathy is associated with ocular inflammation, leading to retinal barrier breakdown, macular edema, and visual cell loss. We investigated the molecular mechanisms involved in microglia/macrophages trafficking in the retina and the role of protein kinase Cζ (PKCζ) in this process. Goto...

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Main Authors: Omri, Samy, Behar-Cohen, Francine, de Kozak, Yvonne, Sennlaub, Florian, Mafra Verissimo, Lourena, Jonet, Laurent, Savoldelli, Michèle, Omri, Boubaker, Crisanti, Patricia
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2011
Fag:
Regular Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157258/
https://ncbi.nlm.nih.gov/pubmed/21712024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.04.018
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