Priority Report: Rearrangements and Amplification of IER3 (IEX-1) Represent A Novel And Recurrent Molecular Abnormality In Myelodysplastic Syndromes (MDS)

IER3 (formerly IEX-1) encodes a 27kDa glycoprotein that regulates death receptor-induced apoptosis, interacts with NF-κb pathways, and increases expression rapidly in response to cellular stresses such as irradiation. Animal models, gene expression microarray experiments, and functional studies in c...

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Bibliografiske detaljer
Main Authors: Steensma, David P., Neiger, Jessemy D., Porcher, Julie C., Keats, J. Jonathan, Bergsagel, P. Leif, Dennis, Thomas R., Knudson, Ryan A., Jenkins, Robert B., Santana-Davila, Rafael, Kumar, Rajiv, Ketterling, Rhett P.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157243/
https://ncbi.nlm.nih.gov/pubmed/19773435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-1428
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