The Tryptophan Metabolite 3-Hydroxyanthranilic Acid Plays Anti-Inflammatory and Neuroprotective Roles During Inflammation: Role of Hemeoxygenase-1

Tryptophan metabolism by the kynurenine pathway (KP) is important to the pathogenesis of inflammatory, infectious, and degenerative diseases. The 3-hydroxykynurenine (3-HK) branch of the KP is activated in macrophages and microglia, leading to the generation of 3-HK, 3-hydroxyanthranilic acid (3-HAA...

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Detalhes bibliográficos
Main Authors: Krause, Daniela, Suh, Hyeon-Sook, Tarassishin, Leonid, Cui, Qiao Ling, Durafourt, Bryce A., Choi, Namjong, Bauman, Avital, Cosenza-Nashat, Melissa, Antel, Jack P., Zhao, Meng-Liang, Lee, Sunhee C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2011
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157215/
https://ncbi.nlm.nih.gov/pubmed/21855684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.05.048
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