Standardization of Epidermal Growth Factor Receptor (EGFR) Measurement by Quantitative Immunofluorescence and Impact on Antibody-Based Mutation Detection in Non–Small Cell Lung Cancer

Challenges in measurement of epidermal growth factor receptor (EGFR) protein expression have led to conflicting data on its prognostic value and discontinuation of its use for prediction of response. Herein is described a quantitative standardized assay for EGFR and its use in a series of retrospect...

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Detalhes bibliográficos
Main Authors: Dimou, Anastasios, Agarwal, Seema, Anagnostou, Valsamo, Viray, Hollis, Christensen, Stephen, Gould Rothberg, Bonnie, Zolota, Vassiliki, Syrigos, Konstantinos, Rimm, David L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2011
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157192/
https://ncbi.nlm.nih.gov/pubmed/21722621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.04.031
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