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Pharmacological elevation of anandamide impairs short-term memory by altering the neurophysiology in the hippocampus

In rodents, many exogenous cannabinoid agonists including Δ(9)-THC and WIN 55,212-2 (WIN-2) have been shown to impair short-term memory (STM) by inhibition of hippocampal neuronal assemblies. However, the mechanisms by which endocannabinoids such as anandamide and 2-arachidonylglycerol (2-AG) modula...

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Detalhes bibliográficos
Main Authors: Goonawardena, Anushka V, Sesay, John, Sexton, Cheryl Ann, Riedel, Gernot, Hampson, Robert E
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156972/
https://ncbi.nlm.nih.gov/pubmed/21767554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2011.07.003
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