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Significant associations of PAI-1 genetic polymorphisms with osteonecrosis of the femoral head

BACKGROUND: The pathogenesis of osteonecrosis of the femoral head (ONFH) has been implicated in hypofibrinolysis and blood supply interruption. Previous studies have demonstrated that decreased fibrinolytic activity due to elevated plasminogen activator inhibitor-1 (PAI-1) levels correlates with ONF...

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Detalhes bibliográficos
Main Authors: Kim, Hye- Ok, Cho, Chang- Hoon, Cho, Yoon- Je, Cho, Seong- Ho, Yoon, Kyung- Sik, Kim, Kang- Il
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156806/
https://ncbi.nlm.nih.gov/pubmed/21752301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2474-12-160
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