Intravitreal homocysteine-thiolactone injection leads to the degeneration of multiple retinal cells, including photoreceptors

PURPOSE: Hyperhomocysteinemia is known to cause degeneration of retinal ganglion cells, but its influence on photoreceptors remains largely unknown. In particular, the role of homocysteine-thiolactone (Hcy-T)—the physiologic metabolite of homocysteine that has been proven to be more cytotoxic than h...

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Main Authors: Chang, Han-Hsin, Lin, David Pei-Cheng, Chen, Ying-Shan, Liu, Hsiang-Jui, Lin, Wei, Tsao, Zih-Jay, Teng, Mei-Ching, Chen, Bo-Yie
Format: Artigo
Jezik:Inglês
Izdano: Molecular Vision 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156793/
https://ncbi.nlm.nih.gov/pubmed/21850169
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