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Longevity in Mice Is Promoted by Probiotic-Induced Suppression of Colonic Senescence Dependent on Upregulation of Gut Bacterial Polyamine Production

BACKGROUND: Chronic low-grade inflammation is recognized as an important factor contributing to senescence and age-related diseases. In mammals, levels of polyamines (PAs) decrease during the ageing process; PAs are known to decrease systemic inflammation by inhibiting inflammatory cytokine synthesi...

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Detalhes bibliográficos
Main Authors: Matsumoto, Mitsuharu, Kurihara, Shin, Kibe, Ryoko, Ashida, Hisashi, Benno, Yoshimi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156754/
https://ncbi.nlm.nih.gov/pubmed/21858192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023652
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