Maternal diet, aging and diabetes meet at a chromatin loop

We have recently demonstrated that exposure to a suboptimal diet during early development leads to abnormal epigenetic regulation of a promoter-enhancer interaction at the gene encoding HNF-4α, a key transcription factor required for pancreatic β-cell differentiation and glucose homeostasis. In addi...

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Bibliografske podrobnosti
Main Authors: Ozanne, Susan E., Sandovici, Ionel, Constância, Miguel
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2011
Teme:
Research Perspective
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156605/
https://ncbi.nlm.nih.gov/pubmed/21623004
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