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Mitochondria in Apoptosis: Bcl-2 family Members and Mitochondrial Dynamics

Mitochondria participate in apoptosis through a range of mechanisms that vary between vertebrates and invertebrates. In vertebrates, they release intermembrane space proteins, such as cytochrome c, to promote caspase activation in the cytosol. This process is the result of the loss of integrity of t...

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Bibliographic Details
Main Authors: Martinou, Jean-Claude, Youle, Richard J.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156409/
https://ncbi.nlm.nih.gov/pubmed/21763611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2011.06.017
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