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Development of a fluorogenic sensor for activated Cdc42
Cdc42, a member of the Rho GTPase family, is a fundamental regulator of the actin cytoskeleton during cell migration. To generate a sensor for Cdc42 activation, we employed a multi-pronged approach, utilizing cysteine labeling and expressed protein ligation, to incorporate the environment sensitive...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3156282/ https://ncbi.nlm.nih.gov/pubmed/21549598 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2011.04.051 |
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