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Evolution of a derived protein–protein interaction between HoxA11 and Foxo1a in mammals caused by changes in intramolecular regulation

Current models of developmental evolution suggest changes in gene regulation underlie the evolution of morphology. Despite the fact that protein complexes regulate gene expression, the evolution of regulatory protein complexes is rarely studied. Here, we investigate the evolution of a protein-protei...

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Autori principali: Brayer, Kathryn J., Lynch, Vincent J., Wagner, Günter P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156161/
https://ncbi.nlm.nih.gov/pubmed/21788518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1100990108
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