IkappaB kinase beta regulates gastric carcinogenesis via IL-1α expression

To explore the role of IKKβ in gastric carcinogenesis, we established a conditional gastric mucosal epithelium IKKβ knockout mouse (Ikkβ(ΔST)) that did not differ phenotypically or histologically from control mice (Ikkβ(F/F)). Gastric cancer was induced using N-methyl-N-nitrosourea (MNU). After 8 mo...

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Autori principali: Sakamoto, Kei, Hikiba, Yohko, Nakagawa, Hayato, Hayakawa, Yoku, Yanai, Ayako, Akanuma, Masao, Ogura, Keiji, Hirata, Yoshihiro, Kaestner, Klaus H., Omata, Masao, Maeda, Shin
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156098/
https://ncbi.nlm.nih.gov/pubmed/20347815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2010.03.047
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