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The role of DMQ(9) in the long-lived mutant clk-1

INTRODUCTION: Ubiquinone (UQ) is a redox active lipid that transfers electrons from complex I or II to complex III in the electron transport chain (ETC). The long-lived C. elegans mutant clk-1 is unable to synthesize its native ubiquinone, and accumulates high amounts of its precursor, 5-demethoxyub...

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Autores principales: Yang, Yu-Ying, Vasta, Valeria, Hahn, Sihoun, Gangoiti, Jon A., Opheim, Elyce, Sedensky, Margaret M., Morgan, Phil G.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156029/
https://ncbi.nlm.nih.gov/pubmed/21745495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2011.06.009
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