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Osteoclasts Lacking Rac2 Have Defective Chemotaxis and Resorptive Activity
The role of the small Rho GTPase Rac2 in mature osteoclasts has not been extensively studied. Rac2(−/−) mice are of normal size and have normal tooth eruption. However, femoral cortical thickness was significantly greater in Rac2(−/−) compared to wild-type mice, while percent cortical porosity was l...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3155765/ https://ncbi.nlm.nih.gov/pubmed/21110188 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00223-010-9435-3 |
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