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Aberrant interaction of calmodulin with the ryanodine receptor develops hypertrophy in the neonatal cardiomyocyte

We have recently shown that the inter-domain interaction between the two domains of ryanodine receptor (RyR), calmodulin binding domain (CaMBD) and CaM-like domain (CaMLD), activates the Ca(2+) channel, and this process is called ‘formation of activation-link’ [Gangopadhyay, J. P. and Ikemoto, N. (2...

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Bibliografiske detaljer
Main Authors: Gangopadhyay, Jaya P., Ikemoto, Noriaki
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3155653/
https://ncbi.nlm.nih.gov/pubmed/21649588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20110203
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