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SSB Functions as a Sliding Platform that Migrates on DNA via Reptation
SSB proteins bind to and control the accessibility of single stranded (ss) DNA, likely facilitated by their ability to diffuse on ssDNA. Using a hybrid single-molecule method combining fluorescence and force, we probed how proteins with large binding site sizes can migrate rapidly on DNA and how pro...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3155616/ https://ncbi.nlm.nih.gov/pubmed/21784244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.06.036 |
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