SSB Functions as a Sliding Platform that Migrates on DNA via Reptation

SSB proteins bind to and control the accessibility of single stranded (ss) DNA, likely facilitated by their ability to diffuse on ssDNA. Using a hybrid single-molecule method combining fluorescence and force, we probed how proteins with large binding site sizes can migrate rapidly on DNA and how pro...

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Библиографические подробности
Главные авторы: Zhou, Ruobo, Kozlov, Alexander G., Roy, Rahul, Zhang, Jichuan, Korolev, Sergey, Lohman, Timothy M., Ha, Taekjip
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3155616/
https://ncbi.nlm.nih.gov/pubmed/21784244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.06.036
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