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SSB Functions as a Sliding Platform that Migrates on DNA via Reptation

SSB proteins bind to and control the accessibility of single stranded (ss) DNA, likely facilitated by their ability to diffuse on ssDNA. Using a hybrid single-molecule method combining fluorescence and force, we probed how proteins with large binding site sizes can migrate rapidly on DNA and how pro...

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מידע ביבליוגרפי
Main Authors: Zhou, Ruobo, Kozlov, Alexander G., Roy, Rahul, Zhang, Jichuan, Korolev, Sergey, Lohman, Timothy M., Ha, Taekjip
פורמט: Artigo
שפה:Inglês
יצא לאור: 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3155616/
https://ncbi.nlm.nih.gov/pubmed/21784244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.06.036
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