N-Termini of Fungal CSL Transcription Factors Are Disordered, Enriched in Regulatory Motifs and Inhibit DNA Binding in Fission Yeast

BACKGROUND: CSL (CBF1/RBP-Jκ/Suppressor of Hairless/LAG-1) transcription factors are the effector components of the Notch receptor signalling pathway, which is critical for metazoan development. The metazoan CSL proteins (class M) can also function in a Notch-independent manner. Recently, two novel...

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Main Authors: Převorovský, Martin, Atkinson, Sophie R., Ptáčková, Martina, McLean, Janel R., Gould, Kathleen, Folk, Petr, Půta, František, Bähler, Jürg
格式: Artigo
語言:Inglês
出版: Public Library of Science 2011
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3155561/
https://ncbi.nlm.nih.gov/pubmed/21858190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023650
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