Synthesis of Biomolecule-Modified Mesoporous Silica Nanoparticles for Targeted Hydrophobic Drug Delivery to Cancer Cells

Synthetic methodologies integrating hydrophobic drug delivery and biomolecular targeting with mesoporous silica nanoparticles are described. Transferrin and cyclic-RGD peptides are covalently attached to the nanoparticles utilizing different techniques and provide selectivity between primary and met...

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Main Authors: Ferris, Daniel P., Lu, Jie, Gothard, Chris, Yanes, Rolando, Thomas, Courtney R., Olsen, John-Carl, Stoddart, J. Fraser, Tamanoi, Fuyuhiko, Zink, Jeffrey I.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3155389/
https://ncbi.nlm.nih.gov/pubmed/21595023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/smll.201002300
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