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Antiviral Activity and Mechanism of Action of Novel Thiourea Containing Chiral Phosphonate on Tobacco Mosaic Virus

Using half-leaf method O,O′-diisopropyl (3-(L-1-(benzylamino)-1-oxo-3- phenylpropan-2-yl)thioureido)(phenyl)methyl phosphonate (2009104) was studied for its activity on tobacco mosaic virus (TMV). It showed good curative activity in vivo and the curative activity at 500 μg/mL was found to be 53.3%....

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Detalhes bibliográficos
Main Authors: Fan, Huitao, Song, Baoan, Bhadury, Pinaki S., Jin, Linhong, Hu, Deyu, Yang, Song
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3155367/
https://ncbi.nlm.nih.gov/pubmed/21845094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms12074522
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