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Cellular stress response pathways and ageing: intricate molecular relationships

Ageing is driven by the inexorable and stochastic accumulation of damage in biomolecules vital for proper cellular function. Although this process is fundamentally haphazard and uncontrollable, senescent decline and ageing is broadly influenced by genetic and extrinsic factors. Numerous gene mutatio...

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Detalhes bibliográficos
Main Authors: Kourtis, Nikos, Tavernarakis, Nektarios
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3155297/
https://ncbi.nlm.nih.gov/pubmed/21587205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.162
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