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The challenge of developing universal vaccines

Antigenic variability of immunodominant antigens is a common mechanism used by pathogens to escape the immune response. Frequently, the proposed solution is a universal vaccine based on conserved antigens present on all strains of the pathogen. Indeed, a lot of progress has been made in the developm...

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Bibliografiske detaljer
Hovedforfatter: Rappuoli, Rino
Format: Artigo
Sprog:Inglês
Udgivet: Faculty of 1000 Ltd 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3155208/
https://ncbi.nlm.nih.gov/pubmed/21904572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3410/M3-16
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