Studying Gene and Gene-Environment Effects of Uncommon and Common Variants on Continuous Traits: A Marker-Set Approach Using Gene-Trait Similarity Regression

Genomic association analyses of complex traits demand statistical tools that are capable of detecting small effects of common and rare variants and modeling complex interaction effects and yet are computationally feasible. In this work, we introduce a similarity-based regression method for assessing...

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Détails bibliographiques
Auteurs principaux: Tzeng, Jung-Ying, Zhang, Daowen, Pongpanich, Monnat, Smith, Chris, McCarthy, Mark I., Sale, Michèle M., Worrall, Bradford B., Hsu, Fang-Chi, Thomas, Duncan C., Sullivan, Patrick F.
Format: Artigo
Langue:Inglês
Publié: Elsevier 2011
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3155192/
https://ncbi.nlm.nih.gov/pubmed/21835306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2011.07.007
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