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Npp1 promotes atherosclerosis in ApoE knockout mice

Ecto-nucleotide pyrophosphatase/phosphodiesterase 1 (NPP1) generates inorganic pyrophosphate (PP(i)), a physiologic inhibitor of hydroxyapatite deposition. In a previous study, we found NPP1 expression to be inversely correlated with the degree of atherosclerotic plaque calcification. Moreover, func...

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Bibliografiske detaljer
Main Authors: Nitschke, Yvonne, Weissen-Plenz, Gabriele, Terkeltaub, Robert, Rutsch, Frank
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154990/
https://ncbi.nlm.nih.gov/pubmed/21477221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2011.01327.x
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