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Carbohydrate-binding motif in Chitinase 3-like 1 (CHI3L1/YKL-40) specifically activates Akt signaling pathway in colonic epithelial cells

Host-microbial interactions play a key role during the development of colitis. We have previously shown that chinase 3-like 1 (CHI3L1) is an inducible molecule overexpressed in colonic epithelial cells (CECs) under inflammatory conditions. In this study, we found that chitin-binding motif (CBM) of C...

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Detalhes bibliográficos
Main Authors: Chen, Chun-Chuan, Llado, Victoria, Eurich, Katrin, Tran, Hoa T., Mizoguchi, Emiko
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154968/
https://ncbi.nlm.nih.gov/pubmed/21546314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2011.04.007
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