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Glutamine Synthetase Is a Genetic Determinant of Cell Type–Specific Glutamine Independence in Breast Epithelia
Although significant variations in the metabolic profiles exist among different cells, little is understood in terms of genetic regulations of such cell type–specific metabolic phenotypes and nutrient requirements. While many cancer cells depend on exogenous glutamine for survival to justify the the...
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Formato: | Artigo |
Idioma: | Inglês |
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Public Library of Science
2011
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3154963/ https://ncbi.nlm.nih.gov/pubmed/21852960 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002229 |
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