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Structure and Dynamics of the Membrane-Bound Cytochrome P450 2C9
The microsomal, membrane-bound, human cytochrome P450 (CYP) 2C9 is a liver-specific monooxygenase essential for drug metabolism. CYPs require electron transfer from the membrane-bound CYP reductase (CPR) for catalysis. The structural details and functional relevance of the CYP-membrane interaction a...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3154944/ https://ncbi.nlm.nih.gov/pubmed/21852944 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002152 |
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