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The spindle checkpoint protein Mad2 regulates APC/C activity during prometaphase and metaphase of meiosis I in Saccharomyces cerevisiae
In many eukaryotes, disruption of the spindle checkpoint protein Mad2 results in an increase in meiosis I nondisjunction, suggesting that Mad2 has a conserved role in ensuring faithful chromosome segregation in meiosis. To characterize the meiotic function of Mad2, we analyzed individual budding yea...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The American Society for Cell Biology
2011
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3154881/ https://ncbi.nlm.nih.gov/pubmed/21697504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-04-0378 |
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