Gatekeeper of pluripotency: A common Oct4 transcriptional network operates in mouse eggs and embryonic stem cells

BACKGROUND: Oct4 is a key factor of an expanded transcriptional network (Oct4-TN) that governs pluripotency and self-renewal in embryonic stem cells (ESCs) and in the inner cell mass from which ESCs are derived. A pending question is whether the establishment of the Oct4-TN initiates during oogenesi...

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Hlavní autoři: Zuccotti, Maurizio, Merico, Valeria, Bellone, Michele, Mulas, Francesca, Sacchi, Lucia, Rebuzzini, Paola, Prigione, Alessandro, Redi, Carlo A, Bellazzi, Riccardo, Adjaye, James, Garagna, Silvia
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154874/
https://ncbi.nlm.nih.gov/pubmed/21729306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-12-345
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