Association of Human TLR1 and TLR6 Deficiency with Altered Immune Responses to BCG Vaccination in South African Infants

The development of effective immunoprophylaxis against tuberculosis (TB) remains a global priority, but is hampered by a partially protective Bacillus Calmette-Guérin (BCG) vaccine and an incomplete understanding of the mechanisms of immunity to Mycobacterium tuberculosis. Although host genetic fact...

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Detalhes bibliográficos
Main Authors: Randhawa, April Kaur, Shey, Muki S., Keyser, Alana, Peixoto, Blas, Wells, Richard D., de Kock, Marwou, Lerumo, Lesedi, Hughes, Jane, Hussey, Gregory, Hawkridge, Anthony, Kaplan, Gilla, Hanekom, Willem A., Hawn, Thomas R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154845/
https://ncbi.nlm.nih.gov/pubmed/21852947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002174
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