Cytotoxic CD4(+) T cell responses to Epstein-Barr virus contrast with CD8 responses in breadth of lytic cycle antigen choice and in lytic cycle recognition()

Epstein-Barr virus (EBV), a B-lymphotropic herpesvirus, encodes 2 immediate early (IE), >30 early (E) and >30 late (L) phase proteins during its replication (lytic) cycle. Despite this, lytic antigen-induced CD8 responses are strongly skewed towards IE and a few E proteins only, all expressed...

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Autores principales: Long, Heather M., Leese, Alison M., Chagoury, Odette L., Connerty, Shawn R., Quarcoopome, Jared, Quinn, Laura L., Shannon-Lowe, Claire, Rickinson, Alan B.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154640/
https://ncbi.nlm.nih.gov/pubmed/21622860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100590
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