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Improving protein structure prediction using multiple sequence-based contact predictions

Although residue-residue contact maps dictate the topology of proteins, sequence-based ab initio contact predictions have been found little use in actual structure prediction due to the low accuracy. We developed a composite set of nine SVM-based contact predictors which are used in I-TASSER simulat...

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Main Authors: Wu, Sitao, Szilagyi, Andras, Zhang, Yang
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154634/
https://ncbi.nlm.nih.gov/pubmed/21827953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2011.05.004
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