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Cyclic stretch induces alveolar epithelial barrier dysfunction via calpain-mediated degradation of p120-catenin

Lung hyperinflation is known to be an important contributing factor in the pathogenesis of ventilator-induced lung injury. Mechanical stretch causes epithelial barrier dysfunction and an increase in alveolar permeability, although the precise mechanisms have not been completely elucidated. p120-cate...

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Bibliografiska uppgifter
Huvudupphovsmän: Wang, Yuelan, Minshall, Richard D., Schwartz, David E., Hu, Guochang
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Physiological Society 2011
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154624/
https://ncbi.nlm.nih.gov/pubmed/21571907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00048.2011
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