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Deletion of Drosophila muscle LIM protein decreases flight muscle stiffness and power generation

Muscle LIM protein (MLP) can be found at the Z-disk of sarcomeres where it is hypothesized to be involved in sensing muscle stretch. Loss of murine MLP results in dilated cardiomyopathy, and mutations in human MLP lead to cardiac hypertrophy, indicating a critical role for MLP in maintaining normal...

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Detalhes bibliográficos
Main Authors: Clark, Kathleen A., Lesage-Horton, Heather, Zhao, Cuiping, Beckerle, Mary C., Swank, Douglas M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154547/
https://ncbi.nlm.nih.gov/pubmed/21562304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00206.2010
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