Deletion of Drosophila muscle LIM protein decreases flight muscle stiffness and power generation

Muscle LIM protein (MLP) can be found at the Z-disk of sarcomeres where it is hypothesized to be involved in sensing muscle stretch. Loss of murine MLP results in dilated cardiomyopathy, and mutations in human MLP lead to cardiac hypertrophy, indicating a critical role for MLP in maintaining normal...

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Huvudupphovsmän: Clark, Kathleen A., Lesage-Horton, Heather, Zhao, Cuiping, Beckerle, Mary C., Swank, Douglas M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Physiological Society 2011
Ämnen:
Muscle Cell Biology and Cell Motility
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154547/
https://ncbi.nlm.nih.gov/pubmed/21562304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00206.2010
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